In order to improve the Negative Predictive Value of our Urinalysis Reflex to UTI-ID by PCR
Panel, we have added the Catalase test to strengthen our final determination of calling a urine
“negative” and therefore would not reflex it to a UTI-ID by PCR. This was done to minimize the
number of “Negative-Not Detected” urines being reflexed for UTI-ID by PCR analysis.
By the addition of the Catalase to our Reflex to our UA Reflex Panel we have significantly
improved our Negative Predictive Value of a potential UTI to nearly 100% and therefore we can
more confidently rule out the reflex to a UTI-ID by PCR analysis.
Catalase is found in both WBCs and Bacteria. The best Positive Predictive Value of a potential
UTI that would indicate a reflex to a UTI-ID by PCR is the presence of both WBCs (pyuria) and
Bacteria (bacteriuria). Normal, clean urine has no significant Catalase activity.
A UTI-ID by PCR will be reflexively ordered when 1 or more of the following triggers
occurs:
- Clarity- Cloudy (very)
- Blood- Positive
- Nitrite- Positive
- Leukocyte Esterase- Positive
- Catalase- Positive
Ordering Instructions:
- Order the Urinalysis+Catalase w/ Reflex to UTI-ID by PCR panel
- If a UTI by C&S is desired, please write “Do Not Perform UTI-PCR” in the Comments Box